Quiz › question 5 of 12 · Long-acting

Which combination of factors raises the risk of virological failure on long-acting cabotegravir + rilpivirine?

A Age over 50 and male sex B Any two of: rilpivirine resistance mutations, subtype A6/A1, BMI ≥ 30 C CD4 nadir below 200 alone D Previous abacavir hypersensitivity
Correct. The SmPC identifies three baseline factors — archived rilpivirine resistance mutations, HIV-1 subtype A6/A1, and BMI ≥ 30 kg/m². A combination of at least two is associated with failure, more often on 2-monthly than monthly dosing.
Vocabria injection SmPC §4.4
Open the related case in the decision tool ← Previous Next question →