Quiz › question 2 of 12 · Interactions

A patient on rifampicin-based TB treatment needs ART. Which statement is correct?

A Bictegravir can be used at the standard dose B Dolutegravir can be used at 50 mg twice daily C Darunavir/cobicistat is preferred D Rilpivirine is unaffected by rifampicin
Correct. Rifampicin induces metabolism of most antiretrovirals. It is contraindicated with bictegravir, rilpivirine, doravirine, cabotegravir and boosted protease inhibitors. Dolutegravir can be given, but the dose must be doubled to 50 mg twice daily.
Tivicay SmPC §4.2Biktarvy SmPC §4.3
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